Vitamin B12 (cobalamin) is a crucial water-soluble nutrient vital for healthy nerve and blood cells, DNA production, and energy,
obtained from animal products (meat, dairy, eggs) or fortified foods/supplements.
Deficiency, common in vegans or older adults, can cause fatigue, nerve issues, anemia, and mood changes, treated with supplements or injections,
but generally, excess B12 is excreted, making side effects rare, though high doses are used for specific conditions like deficiency.
Benefits & Functions
Nervous System: Maintains healthy nerve and brain cells, crucial for function and development.
Red Blood Cells: Essential for forming red blood cells, preventing anemia.
DNA: Involved in DNA synthesis and cell division.
Energy: Helps convert food into usable energy.
Sources
Animal Products: Meat, poultry, fish, eggs, and dairy.
Fortified Foods: Some cereals, breads, and nutritional yeasts.
Supplements: Available as oral tablets, sublingual drops, or injections.
Deficiency & Risks
Who's at Risk:
Vegans/vegetarians, older adults, people with digestive issues (Crohn's, celiac) or stomach surgery.
Symptoms:
Fatigue, weakness, nerve damage (tingling), cognitive issues, mood changes, and anemia (megaloblastic).
Side Effects & Safety
Generally Safe:
As a water-soluble vitamin, the body excretes excess through urine, limiting toxicity.
High Doses:
Sometimes used for cyanide poisoning or high homocysteine, but evidence for other uses (Alzheimer's, fatigue) is limited.
Recommended Intake
Adults: Around 2.4 micrograms (mcg) daily, with older adults potentially needing more due to absorption issues.